6-benzyl-3-(pyridin-4-yl)-5,6-dihydro-1H-pyrazolo[4,3-g]quinazolin-7(8H)-one
KO-947
CAS: 1695533-89-1
Molecular Formula: C21H17N5O
6-benzyl-3-(pyridin-4-yl)-5,6-dihydro-1H-pyrazolo[4,3-g]quinazolin-7(8H)-one - Names and Identifiers
6-benzyl-3-(pyridin-4-yl)-5,6-dihydro-1H-pyrazolo[4,3-g]quinazolin-7(8H)-one - Physico-chemical Properties
| Molecular Formula | C21H17N5O |
| Molar Mass | 355.39 |
| Density | 1.354±0.06 g/cm3(Predicted) |
| Boling Point | 704.1±60.0 °C(Predicted) |
| pKa | 13.32±0.20(Predicted) |
| Storage Condition | -20℃ |
6-benzyl-3-(pyridin-4-yl)-5,6-dihydro-1H-pyrazolo[4,3-g]quinazolin-7(8H)-one - Preparation solution concentration reference
| 1mg | 5mg | 10mg | |
|---|---|---|---|
| 1 mM | 2.814 ml | 14.069 ml | 28.138 ml |
| 5 mM | 0.563 ml | 2.814 ml | 5.628 ml |
| 10 mM | 0.281 ml | 1.407 ml | 2.814 ml |
| 5 mM | 0.056 ml | 0.281 ml | 0.563 ml |
Last Update：2024-01-02 23:10:35
6-benzyl-3-(pyridin-4-yl)-5,6-dihydro-1H-pyrazolo[4,3-g]quinazolin-7(8H)-one - Reference Information
| biological activity | KO-947 is an effective selective inhibitor of ERK1/2 kinases. KO-947 can block ERK signaling and proliferation of tumor cells with abnormal MAPK pathway signals at low nanomolar concentrations. |
| target | TargetValue ERK () |
| Target | Value |
Last Update：2024-04-10 22:29:15
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Product Name: KO-947 Visit Supplier Webpage Request for quotationCAS: 1695533-89-1
Tel: +86-400-900-4166
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Mobile: +86-18621343501
QQ: 2881950922
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Product Name: KO-947 Visit Supplier Webpage Request for quotationCAS: 1695533-89-1
Tel: +86-18821248368
Email: Int06@meryer.com
Mobile: +86-18821248368
QQ: 495145328
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Spot supply
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Tel: 18301782025
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View History
6-benzyl-3-(pyridin-4-yl)-5,6-dihydro-1H-pyrazolo[4,3-g]quinazolin-7(8H)-one
Methyl 4-chloro-6-oxo-1,6-dihydropyridazine-3-carboxylate
6-Bromo[1,2,4]triazolo[1,5-a]pyridine
1H-1,3-BENZODIAZOL-4-YLMETHANAMINE HCL
tert-butyl (7R,8aS)-7-aminohexahydropyrrolo[1,2-a]pyrazine-2(1H)-carboxylate
(5α)-4,5-Epoxy-3,14-dihydroxy-17-(2-propenyl)-morphinan-6-one Cyclic 1,2-Ethanediyl Acetal
2-[5-amino-4-[3-(1,3-benzodioxol-5-yl)-1,2,4-oxadiazol-5-yl]-3-methylsulfanylpyrazol-1-yl]-N-(3-chloro-4-fluorophenyl)acetamide
5-[(1-allyl-2-methyl-1H-indol-3-yl)methylene]-3-(4-bromobenzyl)-1,3-thiazolidine-2,4-dione
2-ETHYL-1-H-IMIDAZOLE-4(5)-CARBALDEHYDE
Methyl 4-chloro-6-oxo-1,6-dihydropyridazine-3-carboxylate
6-Bromo[1,2,4]triazolo[1,5-a]pyridine
1H-1,3-BENZODIAZOL-4-YLMETHANAMINE HCL
tert-butyl (7R,8aS)-7-aminohexahydropyrrolo[1,2-a]pyrazine-2(1H)-carboxylate
(5α)-4,5-Epoxy-3,14-dihydroxy-17-(2-propenyl)-morphinan-6-one Cyclic 1,2-Ethanediyl Acetal
2-[5-amino-4-[3-(1,3-benzodioxol-5-yl)-1,2,4-oxadiazol-5-yl]-3-methylsulfanylpyrazol-1-yl]-N-(3-chloro-4-fluorophenyl)acetamide
5-[(1-allyl-2-methyl-1H-indol-3-yl)methylene]-3-(4-bromobenzyl)-1,3-thiazolidine-2,4-dione
2-ETHYL-1-H-IMIDAZOLE-4(5)-CARBALDEHYDE